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As one of the previous participants stated it did wonders, however first week experienced extreme pain and then to have metallic mouth - everything tastes bad otherwise not experiencing what others seem to be. Don't know if I would want this shot again - it's been 2 weeks and the metallic mouth seems to be getting worse - hopefully it won't last much longer



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Professor Peto for advice regarding the design and execution of the trial; to Professor Steve Ward (Liverpool University, United Kingdom) for measuring dexamethasone concentrations in vials of placebo and active drug; and to all the patients who participated in the trial.

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Polymorphisms of the IL-23R gene are associated with primary immune thrombocytopenia but not with the clinical outcome of pulsed high-dose dexamethasone therapy.

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